We analyzed the expression of markers of GM-CSF derived macrophages (INHBA, MMP12, and TNFα) and M-CSF derived macrophages (CD209) on CD163+ macrophages, and found a similar expression of GM-CSF- and M-CSF-associated markers in synovial tissue of RA and PsA patients (30) (Figure 1B). This evidence concerns the gene CSF2 and rheumatoid arthritis.