Interestingly, this peak is located within the intergenic region of SMAD2 and ZBTB7C, none of which have been previously associated with any asthma-related trait, even in GWAS analyzing the same study populations (120–122), suggesting that admixture mapping is a powerful approach to identify novel asthma loci in admixed populations (120). Here, SMAD2 is linked to asthma.