Moreover, a study by Rohr et al. (20) recently presented that status of MACC1 expression could stratify stage II colon cancer patients with unfavorable proficient mismatch repair (pMMR) status, and a distinct stage II colon cancer patients with pMMR/MACC1low had a favorable prognosis similar to those with deficient mismatch repair (dMMR). This evidence concerns the gene MACC1 and malignant colon neoplasm.