The study model involves a group of 330 heart failure patients, randomized into three groups: arm 1, including 110 patients with visits to a cardiologist every three months; arm 2, with 110 patients followed through supervised telemonitoring and regularly scheduled care; and arm 3, with 110 who enjoyed interactive follow-up through supervised telemonitoring, regularly scheduled care, and a BNP monitor [15]. The gene discussed is NPPB; the disease is heart failure.