A recent study has demonstrated that the growth and migration of human HCC cells are enhanced by 10-100 μM NaHS and dose-dependently inhibited by 600-1000 μM NaHS through epidermal growth factor receptor/extracellular signal-regulated protein kinase/matrix metalloproteinase 2 and phosphatase and tensin homolog deleted on chromosome ten/protein kinase B (PKB/AKT) signaling pathways [111]. Here, AKT1 is linked to hepatocellular carcinoma.