Accordingly, we assessed the extent of organ injury following CLP and determined that myeloid FtH deficiency was associated with significantly improved preservation of renal function as evidenced by serum creatinine (Figure 1C) and transcutaneous glomerular filtration rate measurement (Figure 1D), lesser hepatic injury (AST, Figure 1E), and preserved circulatory status when compared to FtHfl/fl mice (mean arterial pressure, systolic and diastolic blood pressure, Figures 1F–I). This evidence concerns the gene FTH1 and hyperinsulinemic hypoglycemia, familial, 4.