These include humanized HER2 CARs that were shown to have a central memory phenotype in the context of treating breast cancer xenografts (35); IL13Rα2 CARs that showed proliferation and cytotoxicity in a mouse model of glioblastoma (41); and FAP CARs in IP mouse models of MPM (104). This evidence concerns the gene IL13RA2 and glioblastoma.