Considering the prior researches had shown the genetic background could play important role in TBI outcome (19), the present study hypothesized that mTBI-related imbalance may be associated with genetic variants of ASIC3. The association between 3 possible pathological ASIC3 genetic variants, rs2288645, rs2288646, and rs4148855 and the severity of balance impairment in people of mTBI were investigated by subjective questionnaires and an objective postural stability/sensory integration test. Here, ASIC3 is linked to concussion.