The control group tended to be older, to be more likely with previous diabetes mellitus (DM), to have a lower baseline eGFR, waist, BMI, serum K, Hb, and Hct, to have higher baseline triglyceride and serum phosphate level, and to be less likely to treat with an ACEI or ARB within 1 year prior to the index date compared with the study group. The gene discussed is GSTM1; the disease is diabetes mellitus.