Meanwhile, the heat shock protein 70 (Hsp70) inducer elesclomol, the novel tyrosine kinase inhibitor ponatinib, the heat shock protein 70 (Hsp90) inhibitor tanespimycin, and the mitogen-activated protein kinase inhibitor selumetinib have not been previously studied clinically for their effectiveness against GC. The gene discussed is WNK2; the disease is gastric cancer.