For in vivo animal experiments, when visible tumors were formed, local IR with 6 Gy (2 Gy, 3 times) was fractionally administered on days 0, 2, and 4, and a construct encoding either siCtrl (Luc shRNA) or siERK5 (ERK5 shRNA-2) was injected into the tumor mass on days 1, 3, and 5. This evidence concerns the gene MAPK7 and neoplasm.