TNF and Arthritis: OTULIN‐related autoinflammatory syndrome (ORAS) (also known as otulipenia or autoinflammation, panniculitis and dermatosis syndrome (AIPDS); OMIM ID: 617099) is a potentially fatal, TNF‐driven autoinflammatory disease characterised by sterile systemic inflammation, recurrent high fevers, panniculitis, diarrhoea, arthritis and general failure to thrive (Damgaard et al, 2016; Zhou et al, 2016).