Interestingly, when var transcript levels were correlated with iRBCs binding capacities to HBMEC or HDMEC, it showed a strong positive correlation between % binding attributed to EPCR binding and expression of EPCR‐binding var domains by parasites from cerebral malaria patients, supporting that cerebral malaria is indeed promoted by EPCR binding of parasites to the brain endothelium. This evidence concerns the gene PROCR and cerebral malaria.