CPA1 and Barrett esophagus: We co-cultured these lines in the following combinations: 1) EPC2:EPC2 (squamous:squamous, as a normal control); 2) EPC2:CP-A (squamous:columnar, as in Barrett’s esophagus); and 3) EPC2:OE33 (squamous:cancer, as in EAC) (Figure 1B).