CPA1 and cancer: Interestingly, CP-A:OE33 (Barrett’s:cancer, n = 6) also exhibited a substantial increase in VCC following gap closure (0.03 to 0.17) (Figure 3—figure supplement 8D,E) but no substantial increase was observed for CP-A:CP-A (0.01 to 0.06) (Figure 3—figure supplement 8D,E), confirming this observation was not simply CP-A cell line-specific.