PPRC1 and cancer: Of the tumor types included in our study, the correlation with PPRC1 dependency was particularly strong (<−0.25) in liver, lung and stomach cell lines for temsirolimus sensitivity, lung and stomach cell lines for docetaxel and dactolisib sensitivity and breast cell lines for YK-4–279 sensitivity, but were also held for a number of other solid tumor types (Figure 5—figure supplement 7), suggesting their use across multiple cancer types.