Since the increase of miR-21 is not harmonious during the different status of IGT and T2D [(although in the model adjusted for ROS (data not shown) is leading to miR-21 OR (95% CI) = 1.07 (1.02–1.13), p = 0.0064)] such as those of ROS and inversely for SOD2 (Fig. 1b, c), we sought to identify the best multivariable logistic model for IGT by performing a stepwise logistic regression. This evidence concerns the gene SOD2 and type 2 diabetes mellitus.