A study by Grace et al., (2003) demonstrated that there is expression of p53 protein in the early stages of cervical lesions like CIN I and CIN II whereas some studies have reported that the p53 expression is a late event and was seen in advanced cervical intraepithelial lesion (CIN III) and invasive cancer (Goel et al., 2012). The gene discussed is TP53; the disease is uterine cervix carcinoma in situ.