LGR4, a member of this family of receptors, participates in cell signalling, activating transcription factors related to tumour formation, potentiating the Wnt signalling pathway and playing an important role in the development of multiple organs and cancer progression (Wu et al., 2013; Xiao and Chen, 2015; Xu and Hou, 2017). The gene discussed is LGR4; the disease is neoplasm.