MRC1 and neoplasm: Amongst the detected mutations, only one mutation was previously reported flanking the 12B intronic region of the MLH1 (Case 15) while others were uniquely observed in this current study and never been reported in any other Lynch Syndrome studies as denoted in the MMR Genes Variance Database, International Society for Gastrointestinal Hereditary Tumours Database and Human Gene Mutation Database suggesting that these mutations are novel mutations.