Leptin and its receptor were cytoplasmically expressed in tumor cells and were negative in normal astrocytes as observed in other studies (Riolfi et al., 2010; Garofalo et al., 2006; Ishikawa et al., 2004; Koda et al., 2007; Koda et al., 2007; Koda et al., 2007). The gene discussed is LEP; the disease is neoplasm.