CD4 and AIDS: In the univariate analyses, having age‐related comorbidities (p < 0.001), cART adherence (p < 0.001), mode of HIV exposure (p < 0.001), pre‐ART VL (p = 0.029), pre‐ART CD4 (p < 0.001), initial ART regimen (p = 0.097), hepatitis C co‐infection (p = 0.055), prior AIDS diagnosis (p = 0.018) and ever smoked (p = 0.051) were associated with virological failure, and were thus entered into the multivariate model.