As to the usefulness of lncRNA ITSN1‐2 in disease severity and inflammation assessment, the clinical study about RA elucidates that lnc‐ITSN1‐2 is positively associated with erythrocyte sedimentation rate (ESR), CRP, and disease activity score in 28 joints (DAS28) in RA patients. The gene discussed is ITSN1; the disease is rheumatoid arthritis.