The ROC curve revealed that the AUC of lncRNA ITSN1 and APACHE II score was 0.654 (95% CI: 0.581‐0.726) and 0.549 (95% CI: 0.481‐0.616), respectively, and lncRNA ITSN1‐2 expression present a good value on distinguishing survivors and non‐survivors in sepsis patients, whose sensitivity and specificity at the best cutoff point were 92.1% and 40.4%, respectively, and lncRNA ITSN1‐2 expression was 4.059, which implied that lncRNA ITSN1‐2 might be a prognostic marker in sepsis patients (Figure 3B). The gene discussed is ITSN1; the disease is Sepsis.