APOBEC3G and neoplasm: This occurs via their EVs.44, 52 The budding of viral particles is related to this process, which can also transfer cytosolic cargos and antiviral deaminases (eg, the widely studied antiviral deaminase APOBEC3G) in EVs.53, 54 Moreover, within the inflammatory‐focused tumour microenvironment, EV communication can occur in principle in both directions from activated M1/M2 macrophages32, 33, 36, 37, 40, 41, 42 and from tumour cells to macrophages themselves.56, 57, 58, 59, 60