In human ovarian adenocarcinoma cells exposed to cisplatin, development of drug resistance was associated with increased gene expression of antioxidant enzymes (SOD2, CAT, GPX1, HO‐1) and the transcription factor Nrf2, and decreased expression of NOX5, suggesting an adaptive antioxidant response underlying molecular mechanisms associated with cancer cell resistance to cisplatin (Kalinina et al., 2018). Here, NOX5 is linked to cancer.