NOX5 has also been demonstrated in many non‐immune cells and tissues, including placenta, bone marrow, uterus, stomach, skeletal muscle, cancer cells and hepatocytes and in cells of the cardiovascular system, such as cardiomyocytes, endothelial and vascular smooth muscle cells (Mahbouli et al., 2017; Montezano et al., 2010; Yeung et al., 2016). Here, NOX5 is linked to cancer.