In one study on HIV patients who had been coinfected with T. gondii, researchers measured the IFN-γ expression of stimulated total lysate antigen using PBMCs, both before and after treatment with antiparasitic drugs (sulfadiazine, pyrimethamine, folinic acid, trimethoprim-sulfa-methoxazole, and corticosteroids); the infection's evolution was correlated with the restoration of the IFN-γ response and with decreased inflammation (Meira et al., 2015). This evidence concerns the gene IFNG and infection.