Among the DNA recombination, replication and repair category, the following genes were represented: ATM serine/threonine kinase (ATM), Bloom syndrome, RecQ helicase like (BLM), Breast cancer 2, early onset (BRCA2), BRCA1 interacting protein C-terminal helicase 1(BRIP1), Claspin (CLSPN), Nibrin (NBN), and partner and localizer of BRCA2 (PALB2) (Table 1). The gene discussed is CLSPN; the disease is breast cancer.