In contrast to the clear MyD88-dependence of these chemokines and IFNγ-response genes, the induction of the immunoregulatory cytokine IL-10 and of the enzyme Arginase-1 by NMII was largely independent of MyD88 (Figure 7C), which contrasts to the results obtained with BMM after infection with NMII in vitro (Figure 2). Here, ARG1 is linked to infection.