Differential expression of the three CXCR3 splice variants was reported in ovarian tumors, with overexpression of CXCR3alt and CXCR3A vs. normal tissue, while CXCR3B was downregulated vs. normal tissue, suggesting that a specific pattern of CXCR3 RNA transcript processing and expression favors tumor progression and metastasis (83). The gene discussed is CXCR3; the disease is ovarian neoplasm.