APOA5 and metabolic syndrome: Le Chatelier et al. (2013) have found that reduced diversity in the gut microbiota is related with adiposity, insulin resistance and dyslipidemia. Decreased intestinal flora diversity can also be seen in metabolic syndrome alone, which is associated with genetic variation of the apolipoprotein A5 gene. In addition, Lactobacillus has been found to be correlated with central adiposity, fasting blood sugar and negatively correlated with HDL-C levels (Lim et al., 2017).