INS and polycystic ovary syndrome: Changes in diet that increase the protein/carbohydrate ratio have been shown to have small metabolic and reproductive improvements in PCOS patients (Moran et al., 2003), while obese women with PCOS treated with a 1,000 kcal, low fat diet for 6–7 months showed body weight (BW) loss on the order of 5–10% and considerable reductions in the clinical manifestations of PCOS by restoring ovulation, increasing the pregnancy rate, and reducing levels of insulin and androgens (Kiddy et al., 1992).