AIB1 (high vs. low) was associated with BCM with 10-year FU (HR 3.2, 95% CI 1.4–7.8, P = 0.008), but the effect and the evidence was weaker when analyzed with 25-year FU (HR 2.0, 95% CI 0.87–4.8, P = 0.10) (Fig. 3; Table 4). The gene discussed is NCOA3; the disease is blue cone monochromacy.