STING1 and infection: The intracellular molecule STING (Stimulator of interferon genes, also known as MPYS, ERIS, MITA, and TMEM173) is indispensable for the induction of type I interferons (IFNs, e.g., IFNα/β) in response to infection with DNA-based viruses1–3 and with bacteria such as Listeria monocytogenes,4 as demonstrated using both in vitro and in vivo experimental approaches.