IL6 and pancreatic adenocarcinoma: Dandrea et al. (2009) [99] demonstrated that IL6 repression in pancreatic adenocarcinoma cell lines is facilitated by binding of methyl-CpG-binding protein (MeCP2) and H3meK9 to the methylated CpGs spanning from positions − 666 to − 426 relative from the transcription start site of IL6. Interestingly, rs1800796 and cg01770232 is located at position 572 and 662 respectively, and it is therefore possible that rs1800796 alters the binding of MeCP2 and H3meK9 to cg01770232, thereby affecting IL6 expression and DNA methylation, though this has not been tested in placental tissue.