If the SLC16A3-216 intron 1/2 (AC132872.4-202)-hosted ORF_MIN212 is selectively synthesized in healthy cells, and given the potential tumor suppressor function of its highly homologous protein AAL55828.1 (Zhou et al., 2000; unpublished data) (Figure 7), a role could be given in ORF_MIN212 to inhibiting skin cancer. This evidence concerns the gene SLC16A3 and skin neoplasm.