To reinforce the mechanistic value of the retained intron-derived miRNAs (Figure 4A and Table 1), the expression profiles of PRR11 (implicated in cell cycle progression and epithelial to mesenchymal transition [57,58,59]) and CAMK1D (controls mitotic entry of endothelial cells, angiogenesis and epithelial to mesenchymal transition [60,61,62]) genes were investigated both in non-melanoma and melanoma specimens. This evidence concerns the gene PRR11 and melanoma.