AFP and Hepatic fibrosis: Eighty-four percent (76/90) of the patients were infected with genotype C HBV, while the others were infected with genotype A or B. Male sex, low platelets, low albumin, high alpha fetoprotein (AFP, a tumor marker for HCC), high Fibrosis-4 (FIB-4, an indicator of liver fibrosis) index and HCC history were observed more frequently in the liver cirrhosis group than the inactive carrier and chronic hepatitis groups (Table 1).