Some adhesion molecules play an important role in tumor recurrence, metastasis, and invasion.(Okegawa, Pong, Li, & Hsieh, 2004) Based on the construction of PPI network and module analysis, ACAA1, ACADSB, ALDH6A1, AUH, HADH,and PCCA with high degree of connectivity were selected as hub genes. This evidence concerns the gene PCCA and neoplasm.