HADH and neoplasm: Some adhesion molecules play an important role in tumor recurrence, metastasis, and invasion.(Okegawa, Pong, Li, & Hsieh, 2004) Based on the construction of PPI network and module analysis, ACAA1, ACADSB, ALDH6A1, AUH, HADH,and PCCA with high degree of connectivity were selected as hub genes.