MARCHF1 and neoplasm: The apparent diffusion coefficient (ADC), a quantitative parameter of DW‐MRI, has been found to enable the assessment of tumour cellularity, necrosis, cell apoptosis and cell density, which is often used as a useful non‐invasive biomarker for the early detection of treatment response.22, 23, 24 Therefore, MRI was firstly used to elucidate the responses of the tumours to the treatment of MARCH1 siRNA in our study.