Like P53, miR‐34a was reported to promote multiple complications of DM, including nephropathy, endothelial dysfunction and neuropathy.39, 40 As P53/miR‐34a activation leads to DM and its complications, inhibition of P53/miR‐34a may produce beneficial effects on multiple organs/tissues in diabetic individuals. The gene discussed is TP53; the disease is Nephropathy.