CASC2 and gallbladder cancer: Besides, they can act as ceRNAsor as miRNA sponges adsorbing onto the binding sequence of miRNAs.34 For example, lncRNA GAS5 levels were significantly reduced in prostate cancer, and GAS5 overexpression can inhibit tumour progression in part through its inhibitory effects on the expression and activity of miR‐103.35 Similar reports indicated that CASC2 could function as a ceRNA to modulate miR‐181a and promote glioma growth and sensitize glioma cells to TMZ.36 Ma et al37 revealed a reciprocal repression between lncRNA GCASPC and miR‐17‐3p in gallbladder cancer.