To further elucidate the role of WISP3 in HCC cell growth and migration, we employed siRNA (shWISP3 6# and shWISP3 8#) to knock down the expression of endogenous WISP3 in QSG‐7701 and LO2 cells (Figure 3A). The gene discussed is CCN6; the disease is hepatocellular carcinoma.