To explore the potential roles of WISP3 in HCC, we first examined its expression in normal hepatic cell lines (QSG‐7701 and LO2) and HCC cell lines (SMMC‐7721, SK‐HEP‐1, PVTT‐1, Huh7, Hep3B) by Western blot (Figure 1A). The gene discussed is CCN6; the disease is hepatocellular carcinoma.