Since Grin2b encodes a critical subunit of N-methyl-D-aspartate receptor (NMDAR), an important glutamate receptor involved in learning/memory and a variety of neurological disorders including autism and schizophrenia [20, 31], TBR1 regulates neuronal activity and functions by controlling Grin2b expression. The gene discussed is GRIN2B; the disease is schizophrenia.