PKD1 and PKD2 are often the only genes tested when evaluating a patient with a positive family history of ADPKD at the patient age of 20–21 years of age or a patient presenting with accidental findings of renal cysts on imaging or symptomatic manifestations of renal cysts, such as nephrolithiasis or hematuria (Cadnapaphornchai, 2015). Here, PKD2 is linked to cystic kidney disease.