Of 37 patients who were diagnosed as initially resectable metastatic disease, three patients did not undergo R0 resection because of progressive disease after preoperative chemotherapy; ARID1A and ATM mutations were significantly associated with progressive disease (P = 0.026 and P = 0.042, respectively), however, no significant differences were observed in the other genetic alterations at frequency of more than 10%. Here, ATM is linked to metastatic neoplasm.