WNT5A and gastric cancer: To validate our previous findings of the importance of a WNT5A/HNF4α signalling cascade, to GC progression,17 we stably transfected GC cell lines (AGS, SNU1750, MKN45, NCC24, NCI-N87, and NCC59) with a TCF/LEF-luc reporter or empty vector, to quantify possible WNT pathway downregulation.