ACTC1 and familial dilated cardiomyopathy: Familial DCM counts for more that 50% of all cases reported of DCM, and most of them are associated with genetic variations of single genes including, ACTC1, RBM20, MYBPC3, MYH6, MYH7, TNNT2, TPM1, SCN5A, FHOD3, SLC39A8, MLIP, ALPK3, or BAG3 [2,22].