Familial DCM counts for more that 50% of all cases reported of DCM, and most of them are associated with genetic variations of single genes including, ACTC1, RBM20, MYBPC3, MYH6, MYH7, TNNT2, TPM1, SCN5A, FHOD3, SLC39A8, MLIP, ALPK3, or BAG3 [2,22]. This evidence concerns the gene MYBPC3 and familial dilated cardiomyopathy.