With the aim of exploring the effect of LINC00968 and WNT2 on breast cancer cell apoptosis, flow cytometry was employed to analyze the apoptosis rate, and RT-qPCR and Western blot analysis were conducted to measure the expression of apoptosis-related proteins (Bax, cleaved-PARP, cleaved-caspase3 and Bcl-2) in parent MCF-7 cells and drug-resistant MCF-7/ADM cells after plasmid delivery in each group. This evidence concerns the gene WNT2 and breast carcinoma.