Within the SCD group, there were no significant differences between those with pathological levels of T-tau and/or P-tau (n = 9) and those with normal CSF levels, for either CSF sTREM2, YKL-40, MCP-1, clusterin, or fractalkine (independent samples T-test), nor no significant correlations between CSF MCP-1 or clusterin and T-tau or P-tau. Here, CHI3L1 is linked to Schnyder corneal dystrophy.