We studied HuT78, a CD4+ cutaneous T cell lymphoma cell line, which was previously used to identify A3G as a restriction factor for vif-deficient HIV-1 [16], and JVM2, a B cell mantle cell lymphoma cell line carrying t(11;14)(q13; q32) translocation [36]. Here, CD4 is linked to primary cutaneous T-cell non-Hodgkin lymphoma.