Compared with the blank and NC groups, tumor volume was found to be exhibit reduction from the 8th to the 14th d in the miR-506 mimic and siRNA-LHX2 groups, but increased from the 4th to the 14th d in the miR-506 inhibitor group (all p < 0.05); no obvious changes regarding tumor volume were detected in the miR-506 inhibitor + siRNA-LHX2 groups (p > 0.05). The gene discussed is LHX2; the disease is neoplasm.