Compared with the blank and NC groups, the cell invasion ability was found to be weakened in the miR-506 mimic and siRNA-LHX2 groups, while enhanced in the miR-506 inhibitor group (all p < 0.05); no differences regarding cell invasion abilities were observed among the blank, NC and miR-506 inhibitor + siRNA-LHX2 groups as well as between the miR-506 mimic and siRNA-LHX2 groups (all p > 0.05); as expected, the aforementioned results were similar to the results obtained from the 5-8F NPC cell line following transfection as depicted in Fig. 10b. This evidence concerns the gene LHX2 and nasopharyngeal carcinoma.