ADAM33 and asthma: At present, more than 100 single-nucleotide polymorphisms (SNPs) of the ADAM33 gene have been reported to be associated with asthma and related traits: V4 (rs2787094, 3’UTR, C/G), T + 1 (rs2280089, intron, G/A), T2 (rs2280090, cytoplasmatic domain, G/A), T1 (rs2280091, cytoplasmatic domain, A/G), S2 (rs528557, transmembrane domain, G/C), S1 (rs3918396, transmembrane domain, G/A), Q1 (rs612709, intron, G/A), F + 1 (rs511898, intron, C/T), S + 1 (rs2853209, intron, A/T) and so on.