For example, Wang et al. indicated that total glucosides of paeony (TGP) inhibited the LPS-induced production of inflammatory cytokines in OLP by suppressing NF-κB signaling pathway.37 Another report proved that miR-125b was involved in the LPS-induced keratinocyte HaCaT cell proliferation inhibition and apoptosis in OLP via targeting MP-2 expression through PI3K/AKT/mTOR pathway.38 More research works or in vivo animal experiments are needed to further verify the anti-inflammatory effect of AP on CLP in the future. Here, AKT1 is linked to oral lichen planus.